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KMID : 0380020100250040303
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Korean Journal of Biotechnology and Bioengineering
2010 Volume.25 No. 4 p.303 ~ p.310
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Development of Probiotic Products and Challenges
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Seo Jae-Gu
Lee Gwa-Soo
Kim Jin-Eung
Chung Myung-Jun
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Abstract
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Probiotics beneficially affect the health of the host via various mechanisms in the intestine. Recent developments in probiotic products have mainly been made to maximize probiotic effects in human. In this regard, probiotic products containing doubly coated or encapsulated cells, multi-species probiotics, or high viable cell number (1010 viable cells/gram or more) have been developed and are already available in the market. Until now, the majority of probiotics contain live cells but little attention has been paid to other alternative products such as heat-killed cell or bacteriocin-containing ones, which could have broad applications due to advantages over live cell-based probiotics, such as safety and stability. In addition, genetically engineered lactic acid bacteria could be of great importance in the field of alimentary health if they are carefully designed for biological safety. Although a number of probiotics are marketed by claiming health benefits, regulations for health claims will be more stringent. Therefore sufficient scientific and clinical evidences supporting the safety and efficacy of the potential probiotic strain will be required by the regulatory authority for a health claim, which thus may have a huge impact on the future probiotic market.
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KEYWORD
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Probiotics, Lactic acid bacteria, Probiotic effect, European Food Safety Authority, Health claim
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